当前位置:首页>>教师信息 教师信息

刘西岗

发布时间:2020-10-27

刘西岗


博士、教授、博士生研究生导师

电子邮件:xgliu@hebtu.edu.cn

所属专业:植物发育生物学

研究生招生方向:

博士,植物发育生物学、作物学

硕士,植物发育生物学

学习经历:  

09/1993-07/1997 学士   专业: 生物学          6165金沙官方入口生物系

09/1998-08/2000 硕士   专业: 分子细胞生物学  6165金沙官方入口生命科学院

09/2000-07/2004 博士   专业: 分子细胞生物学  6165金沙官方入口生命科学院

工作经历:

08/1997-08/1998   教师                    河北深州中学

08/2004-10/2007   博士后  植物细胞生物学  北京生命科学研究所

11/2007-08/2009   博士后  植物发育生物学  美国加州大学河滨分校植物系

09/2009-09/2012   Research Specialist Ⅲ  美国加州大学河滨分校植物系

10/2012-05/2016   研究员 博士生导师 植物发育生物学 中科院农业资源研究中心

05/2016-05/2020   研究员 中国科学院大学现代农学院教授;中科院农业资源研究中心党委委员;遗传与分子育种研究室主任;中科院遗传发育所学术委员会委员

06/2020-至今  教授 博士生导师 版权所有 :金沙(6165-VIP百度认证)总站线路检测-官方入口

主要研究方向:

植物分生组织维持及分化的分子网络调控机制

植物体所有胚后发育的器官都是由植物各级分生组织分化发育而来。分生组织的产生、维持及分化受到精细的程序化调控。本课题组的研究兴趣之一为系统解析植物各级分生组织包括根尖分生组织、茎尖分生组织及花分生组织中在活性维持及分化特别是响应外界环境如植物激素、光温信号等的多分子调控网络;器官发生发育的分子机制。

作物高产稳产的功能基因组研究

作物的产量关乎国家粮食安全。产量性状三要素中穗粒数和亩穗数直接决定与植物的分生组织活性,而穗粒数和粒重成负相关关系。同时农业生产受到极端环境如干旱、高低温等环境的影响极大。本课题组研究兴趣之一是复杂生产环境下作物小麦、谷子等的高产稳产的功能基因组研究。通过基因克隆、功能研究、机制解析、优异单倍型分析及功能标记开发,为创制新种质提供理论基础和材料。

科研项目:

个人承担:

国家自然科学基金面上项目,32270340,生长素反应因子ARF3调控拟南芥器官原基发生的分子机制及调控网络研究,2023/01-2026/12,54万,主持;

河北省创新研究群体项目,C2021205013,小麦节水耐热的功能基因组研究及应用,2021/01-2023/12,600万,主持;

河北省全职引进高端人才项目,2020HBQZYC004,小麦水分高效利用的分子机制解析及应用,2021/01-2023/12,400万,主持;

国家自然科学基金面上项目,31970824,ASD1(Activated SAM in Darkness1)调控植物暗形态建成中茎尖分生组织活性的分子机制研究,2020/01-2023/12,60万,主持;

国家自然科学基金面上项目,31671354,植物分生组织中染色质环调控WUSCHEL基因表达的分子机制解析,2017/01-2020/12,65万,主持;

国家重点研发计划“主要农作物产量性状形成的分子基础”,2016YFD0100400,增加籽粒数的分子调控机制,2016/07-2020/12,100万,子课题主持;

国家自然科学基金面上项目,31471168,生长素反应因子ARF3介导的植物花干细胞维持及分化的网络解析,2015/01-2018/12,88万,主持;

科技部973重大专项,小麦产量和品质性状的全基因组选择研究,2014CB138100,小麦穗粒数决定基因的克隆及功能研究,2014/01-2018/12,100万,子课题主持;

国家自然科学基金专项基金,31340056,生长素响应因子参与的植物花干细胞维持的分子机理研究,2014/01-2014/12,15万,主持;

2014年 中国科学院“百人计划”A类,250万。 2018年终期评估优秀;

课题组承担:

国家重点研发计划“杂粮作物抗逆和品种形成与调控”,2018YFD1000700,谷子株型及叶夹角关键基因克隆解析,2018/07-2022/12,子课题主持;

国家自然科学基金面上项目, 31871634,谷子CDL1(Curvy and Droopy Leaf 1)调控株型的分子机制研究,2019/01-2022/12,主持;

国家自然科学基金青年项目, 31701423, TabHLH27和TabHLH92在协同逆境响应和小麦穗粒数调控中的功能和机制解析,2018/01-2020/12,主持;

国家自然科学基金青年项目, 31500985, FHY3介导的拟南芥花发育的网络解析,2016/01-2019/12,主持;

国家自然科学基金青年项目, 31401039,拟南芥DNA拓扑异构酶TOP1α通过对细胞分裂素基因的表观调控影响RAM维持的分子机制研究,2015/01-2017/12,主持

代表性研究论文:

Zhang K*., Zhang H., Pan Y., Niu Y., Guo L., Ma Y., Tian S., Wei J., Wang C., Yang X., Fu Y., Qu P., Liu L., Zhang Y., Sun H., Bai Z., Dong J., Li C. *, Liu X*. (2022) Cell- and non-cell-autonomous AUXIN RESPONSE FACTOR3 controls meristem proliferation and phyllotactic patterns. Plant Physiology 2022 Aug 16; kiac370. doi: 10.1093/plphys/kiac370.

Zhang H, Guo L*, Li Y, Zhao D, Liu L, Chang W, Zhang K, Zheng Y, Hou J, Fu C, Zhang Y, Zhang B, Ma Y, Niu Y, Zhang K, Xing J, Cui S, Wang F, Tan K, Zheng S, Tang W, Dong J*, Liu X*. (2022) TOP1α fine-tunes TOR-PLT2 to maintain root tip homeostasis in response to sugars. Nat Plants. 8(7):792-801.

Wang Y, Du F, Wang J, Wang K, Tian C, Qi X, Lu F, Liu X, Ye X, Jiao Y. (2022) Improving bread wheat yield through modulating an unselected AP2/ERF gene. Nat Plants. 8(8):930-939.

Zhang H, Tang Z, Zhang Y, Liu L, Zhao D, Liu X, Guo L, Dong J. (2022) TOP1α suppresses lateral root gravitropism in Arabidopsis. Plant Signal Behav. 17(1):2098646.

Li Y, Li L, Zhao M, Guo L, Guo X, Zhao D, Batool A, Dong B, Xu H, Cui S, Zhang A, Fu X, Li J, Jing R*, Liu X*. (2021) Wheat FRIZZY PANICLE activates VERNALIZATION1-A and HOMEOBOX4-A to regulate spike development in wheat. Plant Biotechnol J. 19(6):1141-1154.

Ren X, Zhi L, Liu L, Meng D, Su Q, Batool A, Ji J, Song L, Zhang N, Guo L, Liu X, Li J, Zhang W. (2021) Alternative Splicing of TaGS3 Differentially Regulates Grain Weight and Size in Bread Wheat. Int J Mol Sci. 28;22(21):11692.

Wang C, Tang S, Zhang Q, Shang Z, Liu X, Diao X, Zhao M. (2021) Kinase activity is required for the receptor kinase DROOPY LEAF1 to control leaf droopiness. Plant Signal Behav.16(11):1976561.

Zhao, MC; Tang, S ; Zhang, HS; He, MM ; Liu, JH ; Zhi, H ; Sui, Y; Liu, XT ; Jia, GQ ; Zhao, ZY ; Yan, JJ ; Zhang, BC ; Zhou, YH ; Chu, JF; Wang, XC; Zhao, BH; Tang, WQ ; Li, JY ; Wu, CY* ; Liu, XG* ; Diao, XM* (2020) DROOPY LEAF1 controls leaf architecture by orchestrating early brassinosteroid signaling. Proc Natl Acad Sci U S A. 117(35): 21766-21774.

Chang, WW; Guo, YH; Zhang, H; Liu, XG*; Guo, L* (2020) Same Actor in Different Stages: Genes in Shoot Apical Meristem Maintenance and Floral Meristem Determinacy in Arabidopsis. FRONTIERS IN ECOLOGY AND EVOLUTION  DOI: 10.3389/fevo.2020.00089.

Chen LG, Gao Z, Zhao Z, Liu X, Li Y, Zhang Y, Liu X, Sun Y, Tang W*. (2019) BZR1 Family Transcription Factors Function Redundantly and Indispensably in BR Signaling but Exhibit BRI1-Independent Function in Regulating Anther Development in Arabidopsis. Mol Plant. S1674-2052(19)30207-2.

Zheng Y, Liu X*. (2019) Chromatin organization in plant and animal stem cell maintenance. Plant Sci. 281:173-179.

Guo L, Cao X, Liu Y, Li J, Li Y, Li D, Zhang K, Gao C, Dong A, Liu X*. (2018) A chromatin loop represses WUSCHEL expression in Arabidopsis. The Plant J. 94 (6):1083-1097

Zhang K, Wang R, Zi H, Li Y, Cao X, Li D, Guo L, Tong J, Pan Y, Jiao Y, Liu R, Xiao L, Liu X*. (2018) AUXIN RESPONSE FACTOR3 Regulates Floral Meristem Determinacy By Repressing Cytokinin Biosynthesis and Signaling. Plant Cell. 30(2):324-346.

Li Y, Fu X*, Zhao M, Zhang W, Li B, An D, Li J, Zhang A, Liu R*, Liu X*. (2018) A Genome-wide View of Transcriptome Dynamics During Early Spike Development in Bread Wheat. Sci Rep. 18;8(1):15338

Fan X, Zhang W, Zhang N, Chen M, Zheng S, Zhao C, Han J, Liu J, Zhang X, Song L, Ji J, Liu X, Ling H, Tong Y, Cui F, Wang T, Li J*. (2018) Identification of QTL regions for seedling root traits and their effect on nitrogen use efficiency in wheat (Triticum aestivum L.). Theor Appl Genet. 131(12):2677-2698.

Zheng Y, Zhang K, Guo L, Liu X*, Zhang Z*. (2018) AUXIN RESPONSE FACTOR3 plays distinct role during early flower development. Plant Signal. Behav. 13(5):e1467690.

Guan C, Wu B, Yu T, Wang Q, Krogan NT, Liu X, Jiao Y*. (2017) Spatial Auxin Signaling Controls Leaf Flattening in Arabidopsis. Curr Biol. 9;27(19):2940-2950.

Li D, Palanca AMS, Won SY, Gao L, Feng Y, Vashisht AA, Liu L, Zhao Y, Liu X, Wu X, Li S, Le B, Kim YJ, Yang G, Li S, Liu J, Wohlschlegel JA, Guo H, Mo B, Chen X, Law JA*. (2017) The MBD7 complex promotes expression of methylated transgenes without significantly altering their methylation status. eLife. 28;6. pii: e19893

Huang Z, Shi T, Zheng B, Yumul RE, Liu X, You C, Gao Z, Xiao L, Chen X*. (2017) APETALA2 antagonizes the transcriptional activity of AGAMOUS in regulating floral stem cells in Arabidopsis thaliana. New Phytol. 15(3):1197-1209.

Li D, Fu X, Guo L, Huang Z, Li Y, Liu Y, He Z, Cao X, Ma X, Zhao M, Zhu G, Xiao L, Wang H, Chen X, Liu R* and Liu X*. (2016) FAR-RED ELONGATED HYPOCOTYL3 activates SEPALLATA2 but inhibits CLAVATA3 to regulate meristem determinacy and maintenance in Arabidopsis. Proc Natl Acad Sci U S A. 113(33):9375-80.

Liu L, Li B, Liu X*. (2016) FAR-RED ELONGATED HYPOCOTYL3 promotes floral meristem determinacy in Arabidopsis. Plant Signal Behav. 11(10):e1238545.

Cao X, He Z, Guo L, Liu X*. (2015) Epigenetic Mechanisms Are Critical for the Regulation of WUSCHEL Expression in Floral Meristems. Plant Physiology 168: 1189-1196.

Liu X*, Dinh TT, Li D, Shi B, Li Y, Cao X, Guo L, Pan Y, Jiao Y, Chen X*. (2014) AUXIN RESPONSE FACTOR 3 integrates the functions of AGAMOUS and APETALA2 in floral meristem determinacy. Plant J. 80(4):629-41.

Liu X, Gao L, Dinh TT, Shi T, Li D, Wang R, Guo L, Xiao L, Chen X*. (2014) DNA topoisomerase I affects polycomb group protein-mediated epigenetic regulation and plant development by altering nucleosome distribution in Arabidopsis. Plant Cell. 26(7):2803-17.

Dinh TT, Gao L, Liu X, Li D, Li S, Zhao Y, O‘Leary M, Le B, Schmitz RJ, Manavella P, Li S, Weigel D, Pontes O, Ecker JR, Chen X*. (2014) DNA topoisomerase 1α promotes transcriptional silencing of transposable elements through DNA methylation and histone lysine 9 dimethylation in Arabidopsis. PLoS Genet. 3;10(7):e1004446 (共同第一作者)

Dinh TT, Luscher E, Li S, Liu X, Won SY, Chen X*. (2014) Genetic screens for floral mutants in Arabidopsis thaliana: enhancers and suppressors. Methods Mol Biol. 1110:127-56.

Li S, Liu L, Zhuang X, Yu Y, Liu X, Cui X, Ji L, Pan Z, Cao X, Mo B, Zhang F, Raikhel N, Jiang L, Chen X*. (2013) MicroRNAs inhibit the translation of target mRNAs on the endoplasmic reticulum in Arabidopsis. Cell. 25;153(3):562-74.

Qiao Y, Liu L, Xiong Q, Flores C, Wong J, Shi J, Wang X, Liu X, Xiang Q, Jiang S, Zhang F, Wang Y, Judelson HS, Chen X, Ma W*. (2013) Oomycete pathogens encode RNA silencing suppressors. Nat Genet. 45(3):330-3.

Yumul RE, Kim YJ, Liu X, Wang R, Ding J, Xiao L, Chen X*. (2013) POWERDRESS and diversified expression of the MIR172 gene family bolster the floral stem cell network. PLoS Genet. 9(1):e1003218.

Dinh TT, O‘Leary M, Won SY, Li S, Arroyo L, Liu X, Defries A, Zheng B, Cutler SR, Chen X*. (2013) Generation of a luciferase-based reporter for CHH and CG DNA methylation in Arabidopsis thaliana. Silence. 4(1):1.

Tang X, Bian S, Tang M, Lu Q, Li S, Liu X, Tian G, Nguyen V, Tsang EW, Wang A, Rothstein SJ, Chen X, Cui Y*. (2012) MicroRNA-mediated repression of the seed maturation program during vegetative development in Arabidopsis. PLoS Genet. 8(11):e1003091.

Dinh TT, Girke T, Liu X, Yant L, Schmid M, Chen X*. (2012) The floral homeotic protein APETALA2 recognizes and acts through an AT-rich sequence element. Development. 139(11):1978-86.

Liu X, Kim YJ, Müller R, Yumul RE, Liu C, Pan Y, Cao X, Goodrich J, Chen X*. (2011) AGAMOUS terminates floral stem cell maintenance in Arabidopsis by directly repressing WUSCHEL through recruitment of Polycomb Group proteins. Plant Cell. 23(10):3654-70.

Ji L, Liu X, Yan J, Wang W, Yumul RE, Kim YJ, Dinh TT, Liu J, Cui X, Zheng B, Agarwal M, Liu C, Cao X, Tang G, Chen X*. (2011) ARGONAUTE10 and ARGONAUTE1 regulate the termination of floral stem cells through two microRNAs in Arabidopsis. PLoS Genet. 7(3):e1001358.

专利:

刘西岗 李永鹏 赵美丞 郭鑫鑫:一种与小麦每穗小穗数相关的SNP位点及其应用 (P) (201910555932)

刘西岗 张腾腾 张琦 郭琳 李永鹏 景瑞莲:小麦每穗小穗数及穗粒数性状相关SNP位点及其应用 (P)(202111027772.0)

刘西岗 赵丹 郭琳 李永鹏 景瑞莲:小麦千粒重性状相关SNP位点及其应用 (P)(202111027769.9)

刘西岗 张琦 郭琳 李永鹏 景瑞莲:小麦单株穗数及耐热性性状相关SNP位点及其应用 (P)(202111026434.5)

刘西岗 齐静 张腾腾 赵丹 郭琳: 小麦每穗小穗数性状相关SNP位点及其应用 (P) (2022100219672)

刘西岗 马玉茹 张腾腾 赵丹 郭琳:小麦千粒重性状相关SNP位点及其应用 (P) (2022100219634)

郭琳 张腾腾 赵丹 刘西岗: 小麦千粒重性状相关SNP位点及其应用 (P) (2022100229886)

社会兼职:

中国植物生理与植物分子生物学学会理事;中国细胞生物学学会植物器官发生分会委员;

河北省植物生理与分子生物学会副理事长;河北省作物学会副理事长;河北省遗传学会副理事长

荣誉奖项:

2018年度          中国科学院“百人计划”终期评估优秀

2017-2018年度     河北“省直先进个人”

2019年            河北省“三三三人才”二层次

2016、2017、2018年度   中科院遗传发育所“先进个人”


学科建设平台